In a big week for Melbourne Storm, Billy Slater will play his 250th first-grade match on Saturday, becoming just the third Storm player to do so.

The Melbourne fullback spoke to the media on Wednesday morning, previewing his milestone match this Saturday at AAMI Park which also coincides with Cameron Smith breaking the club's games record.

"It's a big week for the club, a big week with re-signing Cam, playing my 250th game, our first game at AAMI Park for the year and capped off with Cam breaking the all time games record of Matt Geyer's 262 games," Slater said.

"Milestones come and go, I suppose the memories are what stay with you forever.

"The milestones are the ones that you do remember, its a pretty big milestone for the club this week, hopefully we can make it a special one."

When looking back on his career, Slater highlights his first-grade debut as a standout memory and one that still sticks with him today.

Fan Up and celebrate with Storm on Saturday. Don’t miss this record breaking match as Cameron Smith breaks the club games record and Billy Slater plays his 250th game. Tickets here

"The one game that really stands out would be my first game," Slater said on Wednesday.

"It's a long time ago but I still remember the Round 1 clash in 2003 against Cronulla. 

"That was my debut and I was very fortunate to share that debut with Dallas Johnson as well and Craig Bellamy who was in his first game as head coach of Storm. 

"That was a special occasion and one that certainly stays in the memory bank."