Great mates Billy Slater and Greg Inglis are set to go head-to-head in what promises to be a mouthwatering match-up on Saturday night at AAMI Park.

Speaking following his side's captain's run on Friday afternoon, Bellamy declared Slater and Inglis the game's pre-eminent fullbacks.

"They're obviously great mates," Bellamy said discussing Saturday night't blockbuster fixture.

"They are certainly the two best in their positions anywhere in the world.

Storm take on reigning premiers South Sydney at AAMI Park, Saturday 16 May from 7:30pm. Get your tickets.

"Last week was great to see Billy back.

"He played really well for us and he came through with no problems."

Bellamy praised the Rabbitohs and how Michael Maguire's side has negotiated a tricky start to the year after losing several starters to injury.

"They're not the premiers for no reason, they've obviously got a lot of resilience," Bellamy said.

"They are a big side, the two Burgesses lead that and their other forwards have got good size.

"With a guy like Greg Inglis, it's always tough playing against a side that has got him in it."

With Origin side's selected on Sunday night and squads assembling after Round 10, the NRL competition moves into a crucial period with a number of the league's stars set to miss Club matches while on representative duty.

"Coming into Origin it is a really important game for us," Bellamy said.

"Obviously it is a difficult period to work your way through Origin, Souths will be in the same boat.

Storm will play against the Rabbitohs in the Crown Resorts Foundation Charity Challenge on Saturday night at AAMI Park, raising funds and awareness for Ovarian Cancer Australia. For more details, please click here.